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Diseases Caused by Human Papillomavirus
What are the Diseases Caused by HPV?

HPV can lead to Cervical Cancer and Other Cancers

• Most HPV infections do not progress to cancer. However, those that do cause considerable suffering among patients and their family.

• Half of women afflicted by cervical cancer are between 35 to 55 years of age—the peak years of productivity. Many were probably exposed to one of the high-risk HPV types during their teens or 20s.

• Virtually 100% of cervical cancer cases worldwide (with almost 500,000 new cases and 270,000 deaths each year) are caused by HPV.

• Approximately 40% of vulvar and vaginal cancer cases are caused by HPV.

• Approximately 90% of anal cancer cases are caused by HPV.

• Approximately 40% of penile cancer cases are caused by HPV.

• Approximately 12% of oropharynx (tongue and tonsils) cancer cases and 3% of mouth cancer cases are caused by HPV.

HPV causes Genital Warts

• Genital warts are the most easily-recognized sign of genital HPV infection. They appear within weeks or months after infection, usually within 3 months.

• Two out of three individuals who have sex with a partner with genital warts will develop warts.

• Genital warts appear soft and moist, flesh-colored, in clusters, smooth and flat, or raised with a rough texture.

• In women, genital warts develop on the vulva, cervix, vagina and anus. In men, genital warts can appear around the anus or on the penis, scrotum, groin, or thighs.

HPV causes RRP

• Recurrent respiratory papillomatosis (RRP) is a rare condition in which warty growths develop in the larynx (voice box) of children and young adults. If not surgically removed, the warts can obstruct the airway and cause asphyxiation.

Because of its recurrent nature, RRP may require surgery under general anesthesia as often as every few weeks.

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